Udiliv Tablet – Uses, Side Effects, Dosage, Precautions, and More

Udiliv tablets are widely used in the medical field to treat various liver and gallbladder disorders. The active ingredient in Udiliv is Ursodeoxycholic Acid (UDCA), which helps improve liver function and treat conditions such as primary biliary cirrhosis, gallstones, and certain liver diseases. This article provides an in-depth look at the uses, side effects, dosage, precautions, and more about Udiliv tablets.

Uses of Udiliv Tablet

Udiliv tablets are prescribed for several liver and gallbladder-related conditions, including:

1. Primary Biliary Cirrhosis (PBC)

Udiliv is commonly used to treat PBC, a chronic disease that slowly destroys the bile ducts within the liver. By enhancing bile flow and reducing liver damage, Udiliv helps manage this condition effectively.

2. Gallstones

Udiliv is used to dissolve cholesterol gallstones in patients who are not suitable candidates for surgery. It works by reducing the cholesterol content of bile, making it easier to dissolve the stones.

3. Cholestatic Liver Diseases

Udiliv is beneficial in treating various cholestatic liver diseases where bile flow is impaired. It helps improve bile flow, reduce liver damage, and alleviate associated symptoms.

4. Non-Alcoholic Fatty Liver Disease (NAFLD)

Udiliv is sometimes used in the management of NAFLD, a condition where fat builds up in the liver in people who drink little or no alcohol. It helps improve liver enzyme levels and reduce liver inflammation.

5. Hepatobiliary Disorders

Udiliv is also prescribed for other hepatobiliary disorders, including certain types of chronic hepatitis and conditions involving bile flow obstruction.

How Udiliv Works

The active ingredient in Udiliv, Ursodeoxycholic Acid (UDCA), works by:

• Reducing Cholesterol Absorption: UDCA reduces the absorption of cholesterol from the intestines and decreases the cholesterol content of bile.
• Increasing Bile Flow: It enhances the flow of bile through the liver and gallbladder, reducing bile stasis and promoting the elimination of bile acids.
• Protecting Liver Cells: UDCA has cytoprotective properties that protect liver cells from damage and improve their function.

Dosage of Udiliv Tablet

General Dosage Guidelines

• The dosage of Udiliv depends on the specific condition being treated and the patient’s response to the medication.
• For primary biliary cirrhosis, the usual recommended dose is 13-15 mg per kg of body weight per day, divided into two or three doses.
• For gallstone dissolution, the typical dose is 8-10 mg per kg of body weight per day, usually taken in two or three divided doses.

Administration

• Udiliv tablets should be taken orally with water.
• It is generally recommended to take the medication with food to improve absorption and reduce gastrointestinal side effects.

Missed Dose

• If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for the missed one.

Overdose

• In case of an overdose, seek immediate medical attention. Symptoms of overdose may include diarrhea and severe gastrointestinal discomfort.

Side Effects of Udiliv Tablet

While Udiliv is generally well-tolerated, it can cause side effects in some individuals. Common and rare side effects include:

Common Side Effects

• Diarrhea: The most common side effect is diarrhea, which may be dose-related. If diarrhea persists, consult your healthcare provider.
• Nausea and Vomiting: Some individuals may experience nausea or vomiting, which can be minimized by taking the medication with food.
• Abdominal Pain: Mild abdominal pain or discomfort may occur.

Rare Side Effects

• Allergic Reactions: Symptoms include rash, itching, swelling, severe dizziness, and trouble breathing. Seek medical attention if these occur.
• Liver Function Changes: Rarely, changes in liver enzymes may occur, which should be monitored through blood tests during treatment.
• Gallstone Calcification: In some cases, Udiliv may cause calcification of gallstones, making them less likely to dissolve.

Precautions and Warnings

Before Taking Udiliv

• Allergies: Inform your healthcare provider if you are allergic to Ursodeoxycholic Acid or any other ingredients in Udiliv.
• Medical History: Provide a complete medical history, especially if you have a history of liver disease, gallbladder problems, bile duct obstruction, or pancreatitis.
• Pregnancy and Breastfeeding: Udiliv should be used during pregnancy only if clearly needed. It is not known if Udiliv passes into breast milk, so consult your healthcare provider before breastfeeding.

While Taking Udiliv

• Monitoring: Regular monitoring of liver function tests is recommended during Udiliv therapy to assess the medication’s effectiveness and detect any potential liver-related side effects.
• Diet: Follow a healthy diet as advised by your healthcare provider. In some cases, dietary modifications may be recommended to support liver health.
• Other Medications: Inform your healthcare provider about all the medications you are taking, including prescription, over-the-counter drugs, and herbal supplements. This will help prevent potential drug interactions.

Drug Interactions

• Cholestyramine and Colestipol: These medications can reduce the absorption of Udiliv. If you need to take these drugs, take Udiliv at least 1 hour before or 4-6 hours after these medications.
• Antacids: Certain antacids containing aluminum can decrease the absorption of Udiliv. It is advisable to avoid taking them together.
• Estrogens and Oral Contraceptives: These can increase the risk of cholesterol gallstones and may interfere with the effectiveness of Udiliv in dissolving gallstones.

Storage of Udiliv Tablet

• Store the medication at room temperature away from light and moisture.
• Keep it out of reach of children and pets.
• Do not use the medication after the expiration date mentioned on the packaging.

When to Seek Medical Attention

• Severe Side Effects: Seek immediate medical attention if you experience severe side effects such as difficulty breathing, severe dizziness, signs of a serious allergic reaction, or persistent gastrointestinal discomfort.
• Persistent Symptoms: If your symptoms persist or worsen despite taking the medication, consult your healthcare provider.

Conclusion

Udiliv tablets are an effective treatment option for various liver and gallbladder disorders, including primary biliary cirrhosis, gallstones, and cholestatic liver diseases. While it is generally well-tolerated, it is essential to use Udiliv under the guidance of a healthcare provider to ensure safe and appropriate use. Always follow the prescribed dosage and be aware of potential side effects and interactions with other medications. If you have any concerns or experience any unusual symptoms, do not hesitate to contact your healthcare provider for further advice.

By understanding the uses, side effects, dosage, and precautions associated with Udiliv tablets, patients can make informed decisions about their treatment and work effectively with their healthcare providers to manage their liver and gallbladder conditions.

Also read: Disodium Hydrogen Citrate – Uses, Dosage, Side Effects