Mebeverine : Uses, Side Effects, Dosage, Precautions and More

Mebeverine is a medication commonly used to alleviate symptoms associated with irritable bowel syndrome (IBS) and other gastrointestinal disorders. This comprehensive guide delves into the uses, side effects, dosage, precautions, and more about Mebeverine tablets.

Introduction

Mebeverine is an antispasmodic medication used primarily to relieve symptoms of irritable bowel syndrome (IBS), such as abdominal pain, cramps, and spasms. It works by relaxing the muscles in the gut, thus helping to alleviate the discomfort associated with gastrointestinal disorders. Available in various forms, including tablets, capsules, and suspension, Mebeverine is a widely prescribed medication.

Uses of Mebeverine Tablets

Mebeverine is indicated for the treatment of various gastrointestinal conditions, including:

1. Irritable Bowel Syndrome (IBS): Mebeverine is most commonly used to manage IBS, characterized by symptoms such as abdominal pain, cramping, bloating, gas, and changes in bowel habits.
2. Chronic Irritable Colon: This includes conditions like spastic colitis and mucous colitis, where the colon muscles are prone to spasms and inflammation.
3. Other Functional Bowel Disorders: Mebeverine can be prescribed for other functional gastrointestinal disorders where muscle spasm is a predominant symptom.

How Mebeverine Works

Mebeverine is an antispasmodic agent that works by directly relaxing the smooth muscle in the gut. Unlike other antispasmodics, it does not affect the normal movements of the gut, which means it helps relieve cramps and spasms without causing constipation or impacting normal bowel function. This action makes it particularly useful for individuals with IBS.

Dosage and Administration

Adult Dosage:

• Standard Dosage: The usual dose for adults and children over 10 years of age is one 135 mg tablet taken three times a day. The dosage may vary based on the severity of symptoms and the patient’s response to treatment.
• Sustained Release Capsules: Mebeverine is also available in a 200 mg sustained-release capsule, typically taken twice a day, preferably before meals.

Instructions for Use:

• Timing: It is recommended to take Mebeverine 20 minutes before meals to maximize its effectiveness.
• Administration: Swallow the tablets whole with a glass of water. Do not chew or crush the tablets.
• Missed Dose: If a dose is missed, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for the missed one.

Side Effects of Mebeverine Tablets

Mebeverine is generally well-tolerated, but like all medications, it can cause side effects in some people. Common and less common side effects include:

Common Side Effects:

• Nausea
• Headache
• Dizziness
• Mild skin rash

Rare Side Effects:

• Allergic reactions such as urticaria (hives), angioedema (swelling of the face, lips, or throat), and anaphylaxis (severe allergic reaction)
• Heart palpitations

If any of these side effects persist or worsen, it is important to contact a healthcare professional.

Precautions and Warnings

Before taking Mebeverine, consider the following precautions:

1. Allergies: Inform your doctor if you are allergic to Mebeverine or any other medications.
2. Medical History: Discuss your medical history, especially if you have a history of porphyria (a group of liver disorders) or other serious illnesses.
3. Pregnancy and Breastfeeding: The safety of Mebeverine during pregnancy and breastfeeding has not been fully established. It should be used only if clearly needed and prescribed by a healthcare provider.
4. Drug Interactions: Mebeverine is not known to have significant drug interactions, but it is always best to inform your healthcare provider about all the medications and supplements you are taking.
5. Alcohol: There is no known interaction between alcohol and Mebeverine, but alcohol can irritate the gut, potentially worsening IBS symptoms.

Special Considerations

1. Children: Mebeverine is not recommended for children under 10 years of age due to insufficient evidence regarding safety and efficacy in this age group.
2. Elderly: Elderly patients can take Mebeverine at the same dose as adults. However, they should be monitored closely due to the higher likelihood of concurrent health issues and medications.
3. Liver and Kidney Impairment: There are no specific dosage adjustments required for patients with liver or kidney impairment, but these patients should be monitored for any adverse effects.

Storage and Handling

• Storage: Keep Mebeverine tablets in a cool, dry place away from direct sunlight. Store them at room temperature (below 25°C).
• Handling: Keep the medication out of reach of children and pets. Do not use Mebeverine past its expiration date.

When to Contact a Doctor

While Mebeverine is generally safe, there are specific instances when you should seek medical attention:

• If you experience severe side effects or allergic reactions.
• If symptoms persist or worsen despite taking the medication.
• If you suspect an overdose.

Conclusion

Mebeverine tablets offer significant relief for individuals suffering from IBS and other gastrointestinal disorders characterized by muscle spasms. By understanding its uses, proper dosage, potential side effects, and necessary precautions, patients can effectively manage their symptoms and improve their quality of life. Always consult with a healthcare professional before starting or adjusting any medication to ensure it is appropriate for your specific condition and health profile.

Also read: Amoxicillin Tablet: Uses, Side Effects, Dosage, Precautions and More